Ireland’s healthcare AI landscape is set for an exciting year, with 15 standout innovators poised to make a real impact in 2026. These companies were selected through Health Innovation Hub Ireland’s (HIHI) 2025 AI Call, a national initiative supporting the development and evaluation of artificial intelligence in clinical settings.
Chosen from 44 applications, the winning solutions span Pilot and CE-Ready / Market Entry stages, showcasing a range of innovations—from tools that support clinical decision-making to systems that streamline hospital workflows and enhance patient outcomes.
The selection reflects not only the maturity and diversity of Ireland’s AI healthcare ecosystem, but also the country’s ambition to become a global leader in safe, ethical, and evidence-based digital health technologies. Several of the innovators are already connected to national programs, reinforcing Ireland’s approach of cross-agency collaboration to bring clinically robust AI solutions to the frontline.
As 2026 unfolds, these 15 companies represent the must-watch AI innovators in Irish healthcare, driving forward technologies that could transform patient care, improve system efficiency, and empower clinicians. Their success highlights the potential of AI when combined with ethical frameworks, regulatory support, and strong national innovation pipelines.
For healthcare professionals, investors, and industry watchers, this is your first look at the AI companies shaping the future of Ireland’s healthcare system.
The 15 winning HIHI.AI call winners to watch in 2026, are:
Pilot Category Winners
CommPAL – A web and mobile platform that improves travel, planning, and resource allocation for healthcare workers.
EaseTalk – An AI-powered speech practice platform offering personalised support for people who stutter.
Zendra Health – A clinically validated ADHD assessment tool that uses AI to reduce waiting times, streamlines workflows, and enhances medication management.
PeriVision – A portable AI-enabled device for accurate, efficient functional eye testing.
Deciphex/Diagnexia – An AI-driven digital pathology platform supporting consultant pathologists in colorectal screening.
Katana Healthcare – A point-of-care, AI-supported clinical medication safety system.
Yellow Schedule – Triage Link – An AI-powered triage system improving patient flow and reducing service bottlenecks.
Samsa – AI tools to structure and analyse referral data, supporting clinical decision-making and service improvement.
Alto Health – An AI platform transforming referral and pre-visit workflows to improve patient and clinician experience.
Protostars – An AI platform that automates CE marking audits, compliance processes, and digital health certification.
Qualtate – An AI-native eQMS platform that automates testing, cybersecurity assessments, and generates AI agents for risk and SOP gap analysis.
CE-Ready / Market Entry Category Winners
Praxis AI – A virtual patient simulation platform enhancing clinical reasoning in dental education.
Python AI Solutions – An AI-based diagnostic decision-support tool for cervical screening.
Axial3D – AI-supported 3D modelling for TAVI and EVAR procedural planning.
Genotrial – A real-time, privacy-compliant patient-to-clinical-trial matching platform supporting research acceleration.
HIHI Driving AI Innovation Aligned with National Policy
The HIHI.AI programme directly supports the goals of Ireland’s national AI strategy by ensuring solutions for healthcare are:
trustworthy and human-centred,
clinically validated and regulated,
secure and ethically deployed, and
focused on measurable improvements in patient outcomes and system efficiency.
Through close collaboration with Enterprise Ireland, the Department of Enterprise, Tourism and Employment, the Department of Health and the HSE, HIHI supports the HIHI.AI Call 2025 by offering commercialisation pathways, access to testbeds, clinical partnerships, and guidance on regulatory readiness — enabling AI healthcare innovations to be piloted and evaluated in real-world Irish health settings. These are critical components as Irish AI innovators prepare to scale in a rapidly evolving European AI regulatory environment. The HIHI.AI initiative supports companies developing AI-enabled solutions at various stages of maturity, from early validation to market entry, ensuring safe, effective, and evidence-based adoption within the Irish healthcare ecosystem.
